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Pharmaceutics MCQs

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Pharmaceutics MCQs

What is the primary purpose of enteric coating on tablets?

a) To improve taste
b) To protect the stomach lining
c) To ensure release in the intestine
d) To increase solubility
Answer: c) To ensure release in the intestine

Which of the following is used as a disintegrant in tablet formulation?

a) Lactose
b) Talc
c) Starch
d) Magnesium stearate
Answer: c) Starch

The process of reducing particle size of a solid substance by mechanical means is called:
- a) Levigation
- b) Trituration
- c) Granulation
- d) Pulverization
  Answer: b) Trituration
Which type of emulsions is commonly used for oral administration?
- a) Oil in water (O/W)
- b) Water in oil (W/O)
- c) Multiple emulsion
- d) Microemulsion
  Answer: a) Oil in water (O/W)
Which of the following is an example of a natural suspending agent?
- a) Bentonite
- b) Acacia
- c) Polyvinyl alcohol
- d) Carboxymethyl cellulose
  Answer: b) Acacia
What is the primary function of a buffer in a pharmaceutical solution?
- a) To increase solubility
- b) To maintain pH
- c) To act as a preservative
- d) To enhance taste
  Answer: b) To maintain pH
In tablet manufacturing, which process is used to mix the active ingredient with excipients?
- a) Granulation
- b) Blending
- c) Drying
- d) Coating
  Answer: b) Blending
What is the purpose of adding a lubricant in tablet formulation?
- a) To prevent sticking to the punch and die
- b) To enhance dissolution
- c) To improve hardness
- d) To increase bioavailability
  Answer: a) To prevent sticking to the punch and die
Which of the following is a commonly used preservative in pharmaceutical formulations?
- a) Parabens
- b) Sodium chloride
- c) Glycerin
- d) Sorbitol
  Answer: a) Parabens
Which of the following is a method of sterilization used for thermolabile substances?
- a) Autoclaving
- b) Dry heat
- c) Filtration
- d) Radiation
  Answer: c) Filtration
Which form of dosage is designed for insertion into the rectum?
- a) Tablet
- b) Capsule
- c) Suppository
- d) Syrup
  Answer: c) Suppository
What is the role of a plasticizer in film coating?
- a) To reduce brittleness
- b) To enhance color
- c) To increase disintegration time
- d) To improve solubility
  Answer: a) To reduce brittleness
Which of the following methods is used for the preparation of suspensions?
- a) Levigation
- b) Percolation
- c) Extraction
- d) Distillation
  Answer: a) Levigation
Which of the following is a surfactant used in emulsions?
- a) Sodium lauryl sulfate
- b) Talc
- c) Lactose
- d) Starch
  Answer: a) Sodium lauryl sulfate
In transdermal drug delivery systems, the drug is delivered through:
- a) Oral route
- b) Intravenous route
- c) Skin
- d) Nasal route
  Answer: c) Skin
Which of the following is a common method of tablet coating?
- a) Sugar coating
- b) Film coating
- c) Enteric coating
- d) All of the above
  Answer: d) All of the above
What is the main function of a diluent in tablet formulation?
- a) To bind the ingredients together
- b) To improve the taste
- c) To add bulk to the formulation
- d) To increase disintegration time
  Answer: c) To add bulk to the formulation
Which type of solution is used in intravenous administration?
- a) Isotonic solution
- b) Hypertonic solution
- c) Hypotonic solution
- d) Supersaturated solution
  Answer: a) Isotonic solution
Which of the following is used as a sweetening agent in pharmaceutical formulations?
- a) Saccharin
- b) Sodium benzoate
- c) Propylene glycol
- d) Glycerin
  Answer: a) Saccharin
What is the role of a binder in tablet formulation?
- a) To provide bulk
- b) To hold the ingredients together
- c) To improve dissolution
- d) To enhance taste
  Answer: b) To hold the ingredients together
Which of the following methods is used for the sterilization of ophthalmic solutions?
- a) Autoclaving
- b) Filtration
- c) Dry heat
- d) Radiation
  Answer: b) Filtration
Which of the following is a water-soluble lubricant used in tablet formulation?
- a) Magnesium stearate
- b) Talc
- c) Stearic acid
- d) Polyethylene glycol
  Answer: d) Polyethylene glycol
The term “granulation” in tablet manufacturing refers to:
- a) Coating the tablets
- b) Drying the tablets
- c) Agglomeration of particles
- d) Mixing of ingredients
  Answer: c) Agglomeration of particles
Which of the following is a method used to prepare liposomes?
- a) Solvent evaporation
- b) Spray drying
- c) Hot melt extrusion
- d) Cold compression
  Answer: a) Solvent evaporation
What is the purpose of a humectant in a pharmaceutical formulation?
- a) To increase viscosity
- b) To retain moisture
- c) To improve color
- d) To act as a preservative
  Answer: b) To retain moisture
Which of the following is a common method of sterilization for surgical instruments?
- a) Dry heat
- b) Autoclaving
- c) Filtration
- d) Gas sterilization
  Answer: b) Autoclaving
What is the purpose of using talc in tablet formulation?
- a) As a lubricant
- b) As a diluent
- c) As a binder
- d) As a disintegrant
  Answer: a) As a lubricant
Which of the following is used to measure the viscosity of a liquid?
- a) Pycnometer
- b) Viscometer
- c) Refractometer
- d) Hydrometer
  Answer: b) Viscometer
Which of the following is a preservative used in ophthalmic preparations?
- a) Benzalkonium chloride
- b) Sodium chloride
- c) Glycerin
- d) Ethanol
  Answer: a) Benzalkonium chloride
Which method is used to prepare a syrup?
- a) Filtration
- b) Percolation
- c) Trituration
- d) Decoction
  Answer: b) Percolation
In which dosage form is gelatin commonly used?
- a) Tablets
- b) Capsules
- c) Suppositories
- d) Ointments
  Answer: b) Capsules
Which of the following is a type of suppository base?
- a) Cocoa butter
- b) Lactose
- c) Talc
- d) Sodium benzoate
  Answer: a) Cocoa butter
Which of the following is a polymer used in controlled-release formulations?
- a) Ethyl cellulose
- b) Lactose
- c) Magnesium stearate
- d) Acacia
  Answer: a) Ethyl cellulose
What is the function of a preservative in pharmaceutical formulations?
- a) To increase the shelf life
- b) To improve the taste
- c) To enhance solubility
- d) To act as a thickening agent
  Answer: a) To increase the shelf life
Which of the following is an example of a natural gum used in pharmaceutical formulations?
- a) Xanthan gum
- b) Gelatin
- c) Polyvinyl alcohol
- d) Methylcellulose
  Answer: a) Xanthan gum
Which of the following is commonly used as a plasticizer in the formulation of tablets?
- a) Glycerin
- b) Talc
- c) Magnesium stearate
- d) Calcium carbonate
  Answer: a) Glycerin
The process of converting a liquid into a fine mist for inhalation is called:
- a) Nebulization
- b) Sublimation
- c) Trituration
- d) Percolation
  Answer: a) Nebulization
Which type of granulation involves the addition of a liquid binder to powder to form granules?
- a) Dry granulation
- b) Wet granulation
- c) Direct compression
- d) Fluidized bed granulation
  Answer: b) Wet granulation
Which of the following is an example of a synthetic surfactant used in pharmaceutical preparations?
- a) Sodium lauryl sulfate
- b) Acacia
- c) Tragacanth
- d) Gelatin
  Answer: a) Sodium lauryl sulfate
Which method is used to prepare powders for inhalation?
- a) Spray drying
- b) Freeze drying
- c) Compression
- d) Coacervation
  Answer: a) Spray drying
Which of the following is an example of a binder used in tablet formulation?
- a) Polyvinylpyrrolidone (PVP)
- b) Magnesium stearate
- c) Lactose
- d) Talc
  Answer: a) Polyvinylpyrrolidone (PVP)
Which of the following is an advantage of using a transdermal patch?
- a) Avoids first-pass metabolism
- b) Rapid onset of action
- c) Reduced dosing frequency
- d) Both a and c
  Answer: d) Both a and c
In the context of emulsions, “creaming” refers to:
- a) The separation of the dispersed phase
- b) The breaking of the emulsion
- c) The inversion of phases
- d) The solidification of the oil phase
  Answer: a) The separation of the dispersed phase
Which of the following is used as a flocculating agent in suspensions?
- a) Electrolytes
- b) Surfactants
- c) Polymers
- d) Gums
  Answer: a) Electrolytes
What is the role of an anti-caking agent in powders?
- a) To prevent clumping
- b) To enhance dissolution
- c) To improve taste
- d) To increase density
  Answer: a) To prevent clumping
Which type of dosage form is designed to release the drug slowly over time?
- a) Immediate-release tablet
- b) Sustained-release tablet
- c) Chewable tablet
- d) Effervescent tablet
  Answer: b) Sustained-release tablet
Which of the following is a technique used to improve the solubility of poorly water-soluble drugs?
- a) Micronization
- b) Sublimation
- c) Coacervation
- d) Granulation
  Answer: a) Micronization
Which of the following methods is used for the sterilization of heat-sensitive pharmaceutical products?
- a) Filtration
- b) Autoclaving
- c) Dry heat
- d) Gas sterilization
  Answer: d) Gas sterilization
Which of the following is used as a coating material in enteric-coated tablets?
- a) Hydroxypropyl methylcellulose (HPMC)
- b) Ethyl cellulose
- c) Cellulose acetate phthalate (CAP)
- d) Gelatin
  Answer: c) Cellulose acetate phthalate (CAP)
Which of the following excipients can act as both a binder and a disintegrant in tablet formulation?
- a) Starch
- b) Talc
- c) Magnesium stearate
- d) Calcium carbonate
  Answer: a) Starch
Which of the following is commonly used to enhance the bioavailability of a drug?
- a) Surfactants
- b) Preservatives
- c) Colorants
- d) Flavors
  Answer: a) Surfactants
What is the purpose of using a viscosity enhancer in a liquid dosage form?
- a) To increase the thickness of the solution
- b) To improve the solubility of the drug
- c) To enhance the taste of the formulation
- d) To act as a preservative
  Answer: a) To increase the thickness of the solution
In the context of pharmaceutical aerosols, “propellant” refers to:
- a) The substance that creates pressure to expel the product
- b) The active ingredient
- c) The container material
- d) The flavoring agent
  Answer: a) The substance that creates pressure to expel the product
Which of the following is a method of preparing a soft gelatin capsule?
- a) Rotary die process
- b) Compression molding
- c) Solvent casting
- d) Freeze drying
  Answer: a) Rotary die process
What is the function of a sweetening agent in oral liquid formulations?
- a) To mask the bitter taste of the drug
- b) To act as a preservative
- c) To improve the solubility of the drug
- d) To increase viscosity
  Answer: a) To mask the bitter taste of the drug
Which of the following is an example of an antioxidant used in pharmaceutical formulations?
- a) Ascorbic acid
- b) Sodium chloride
- c) Glycerin
- d) Sorbitol
  Answer: a) Ascorbic acid
In the context of drug stability, “hydrolysis” refers to:
- a) The decomposition of a drug in the presence of water
- b) The oxidation of a drug
- c) The reduction of a drug
- d) The polymerization of a drug
  Answer: a) The decomposition of a drug in the presence of water